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Mediterranean diet intervention alters the gut microbiome in older people reducing frailty and improving health status: the NU-AGE 1-year dietary intervention across five European countries

Gut · 2020 · Vol. 69(7) · pp. 1218–1228

Tarini Shankar Ghosh(University College Cork)Simone Rampelli(University of Bologna)Ian B. Jeffery(University College Cork)Aurelia Santoro(University of Bologna)Marta C. Neto(University College Cork)Miriam Capri(University of Bologna)Enrico Giampieri(University of Bologna)Amy Jennings(University of East Anglia)Marco Candela(University of Bologna)Silvia Turroni(University of Bologna)Erwin G. Zoetendal(Wageningen University & Research)Gerben D. A. Hermes(Wageningen University & Research)Elodie Caumon(Centre de Recherche en Nutrition Humaine d'Auvergne)Nathalie Meunier(Centre de Recherche en Nutrition Humaine d'Auvergne)Corinne Malpuech‐Brugère(Université Clermont Auvergne)Estelle Pujos‐Guillot(Université Clermont Auvergne)A. M. Berendsen(Wageningen University & Research)C.P.G.M. de Groot(Wageningen University & Research)Edith J M Feskins(Wageningen University & Research)Joanna Kałuża(Warsaw University of Life Sciences)Barbara Pietruszka(Warsaw University of Life Sciences)Marta Jeruszka-Bielak(Warsaw University of Life Sciences)Blandine Comte(Université Clermont Auvergne)Monica Maijo-Ferre(Quadram Institute)Claudio Nicoletti(Quadram Institute)Willem M. de Vos(University of Helsinki)Susan J. Fairweather‐Tait(University of East Anglia)Aedín Cassidy(Queen's University Belfast)Patrizia Brigidi(University of Bologna)Claudio Franceschi(N. I. Lobachevsky State University of Nizhny Novgorod)Paul W. O’Toole✉(University College Cork)

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Abstract

Collectively, our findings support the feasibility of improving the habitual diet to modulate the gut microbiota which in turn has the potential to promote healthier ageing.

Gut microbiota and health Nutritional Studies and Diet Diet and metabolism studiesMediterranean dietMicrobiomeGut floraAgeingGerontologyIntervention (counseling)MedicineHealthy ageingPhysiologyBiology