Phytochemical screening, antimicrobial and anticancerous activities of two different plant Extracts

Abstract

The phytochemical screening of ethanolic leaf extract of L. glutinosa and C. quadrangularis confirmed the presence of alkaloids, steroids, flavonoids, terpenoids, tannins, anthraquinones and alkaloids, flavonoids, terpenoids respectively. Disk diffusion method was performed to evaluate the antimicrobial activity of these plant extracts. L. glutinosa showed its highest activity against a gram negative strain S. paratyphi which exhibited a ring of 12 mm in diameter at 400 μg/disc. In the case of C. quadrangularis, highest activity was found against S. paratyphi which showed a ring of 12.33 mm in diameter at 400 μg/disc. On the contrary, standard Kanamycin showed its highest zone of inhibition against E. coli which is 28.66 mm in diameter at 30 μg/disc. In the case of anticancerous activity, standard vincristine sulphate showed 12.59 µg/ml activity whereas ethanolic leaf extract of L. glutinosa & C. quadrangularis demonstrated minimal activity which is 530.05 µg/ml and 639.68 µg/ml respectively.