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Rational approaches, design strategies, structure activity relationship and mechanistic insights for anticancer hybrids

European Journal of Medicinal Chemistry · 2014 · Vol. 77 · pp. 422–487
Kunal NepaliSahil SharmaManmohan SharmaPreet Mohinder Singh BediK.L. Dhar
Synthesis and Biological EvaluationSynthesis and biological activityCancer therapeutics and mechanismsPharmacophoreChemistryRational designComputational biologyHybridIsatinStructure–activity relationshipAnticancer drugTubulinDrug

MeSH terms

AnimalsAntineoplastic AgentsDrug Screening Assays, AntitumorHumansStructure-Activity RelationshipDrug DesignMolecular StructureCell Proliferation
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References
Isolation and structure of the strong cell growth and tubulin inhibitor combretastatin A-4
Cellular and Molecular Life Sciences · 1989 · 785 citations
Angiogenesis in cancer and other diseases
Nature · 2000 · 8,970 citations
Biological effects of resveratrol
Life Sciences · 2000 · 1,655 citations
Plant Foods and Herbal Sources of Resveratrol
Journal of Agricultural and Food Chemistry · 2002 · 990 citations
Designed Multiple Ligands. An Emerging Drug Discovery Paradigm
Journal of Medicinal Chemistry · 2005 · 1,171 citations
HDAC family: What are the cancer relevant targets?
Cancer Letters · 2008 · 1,047 citations
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Rational approaches, design strategies, structure activity relationship and mechanistic insights for anticancer hybrids · Scinovex