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Optimization of the treatment with beta-lactam antibiotics in critically ill patients—guidelines from the French Society of Pharmacology and Therapeutics (Société Française de Pharmacologie et Thérapeutique—SFPT) and the French Society of Anaesthesia and Intensive Care Medicine (Société Française d’Anesthésie et Réanimation—SFAR)

Critical Care · 2019 · Vol. 23(1) · pp. 104–104

Romain Guilhaumou✉(Institut de Neurosciences des Systèmes)Sihem Benaboud(Hôpital Cochin)Youssef Bennis(Centre Hospitalier Universitaire Amiens-Picardie)Claire Dahyot‐Fizelier(Centre Hospitalier Universitaire de Poitiers)Éric Dailly(Centre Hospitalier Universitaire de Nantes)Peggy Gandia(Centre Hospitalier Universitaire de Toulouse)Sylvain Goutelle(Inserm)Sandrine Lefeuvre(Centre hospitalier universitaire d'Orléans)Nicolas Mongardon(Centre Hospitalier Universitaire Henri-Mondor)Claire Roger(Centre Hospitalier Universitaire de Nîmes)Julien Scala‐Bertola(Centre Hospitalier Régional et Universitaire de Nancy)F. Lemaı̂tre(Hôpital Pontchaillou)Marc Garnier(Sorbonne Université)

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Abstract

The experts strongly suggest the use of personalized dosing, continuous or prolonged infusion and therapeutic drug monitoring when administering βLA in critically ill patients.

Antibiotics Pharmacokinetics and Efficacy Pneumonia and Respiratory Infections Antibiotic Use and ResistanceMedicineGuidelineIntensive care medicineIntensive care unitPopulationIntensive careDosingPharmacology

MeSH terms

Anti-Bacterial Agentsbeta-Lactamasesbeta-LactamasesFranceGlomerular Filtration RateHumansIntensive Care UnitsSerum AlbuminSocieties, MedicalSocieties, PharmaceuticalCritical IllnessTreatment OutcomeDrug MonitoringGuidelines as TopicDrug Dosage Calculations

Citations

513

FWCI

38.19

field-weighted impact

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135

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100%

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