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The recent progress of isoxazole in medicinal chemistry

Bioorganic & Medicinal Chemistry · 2018 · Vol. 26(12) · pp. 3065–3075
Jie ZhuJun MoHongzhi LinChen YaoHaopeng Sun
Click Chemistry and ApplicationsSynthesis and Biological EvaluationSynthesis and biological activityIsoxazoleChemistryMoietyBroad spectrumRing (chemistry)Combinatorial chemistryNanotechnologyMedicinal chemistryStereochemistryOrganic chemistry

MeSH terms

Anti-Infective AgentsAntineoplastic AgentsBacteriaCell SurvivalChemistry, PharmaceuticalFungiHumansIsoxazolesNeoplasmsRNA Viruses

Funding

  • National Natural Science Foundation of China
  • Natural Science Foundation of Jiangsu Province
Citations
390
FWCI
13.13
field-weighted impact
References
79
Percentile
99%
vs. same field & year
Citations per year
References
Isolation and structure of the strong cell growth and tubulin inhibitor combretastatin A-4
Cellular and Molecular Life Sciences · 1989 · 785 citations
Hidden Killers: Human Fungal Infections
Science Translational Medicine · 2012 · 4,243 citations
How antibiotics kill bacteria: from targets to networks
Nature Reviews Microbiology · 2010 · 2,185 citations
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The recent progress of isoxazole in medicinal chemistry · Scinovex