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Therapy-Related Clonal Hematopoiesis in Patients with Non-hematologic Cancers Is Common and Associated with Adverse Clinical Outcomes

Cell stem cell · 2017 · Vol. 21(3) · pp. 374–382.e4
Catherine C. CoombsAhmet ZehirSean M. DevlinAshwin KishtagariAijazuddin SyedPhilip JonssonDavid M. HymanDavid B. SolitMark E. RobsonJosé BaselgaMaria E. ArcilaMarc LadanyiMartin S. TallmanRoss L. LevineMichael F. Berger
Acute Myeloid Leukemia ResearchCancer Genomics and DiagnosticsHematopoietic Stem Cell TransplantationBiologyHaematopoiesisHematologyStem cellLeukemiaSomatic evolution in cancerCancerSomatic cellClinical significanceImmunology

MeSH terms

AgedClone CellsFemaleHematopoiesisHumansMaleMiddle AgedMutationRisk FactorsCohort StudiesSurvival AnalysisTreatment OutcomeHematologic NeoplasmsGenetic Association Studies

Funding

  • National Science Foundation
  • Conquer Cancer Foundation
  • Stand Up To Cancer
  • National Cancer Institute
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