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Signatures of mutational processes in human cancer

Nature · 2013 · Vol. 500(7463) · pp. 415–421

Australian Pancreatic Cancer Genome Initiative✉(Wellcome Sanger Institute)Ludmil B. Alexandrov(Wellcome Sanger Institute)ICGC PedBrain(Wellcome Sanger Institute)Serena Nik‐Zainal(BC Cancer Agency)David C. Wedge(Wellcome Sanger Institute)Samuel Aparício(University of British Columbia Hospital)Sam Behjati(University of Cambridge)Andrew V. Biankin(Garvan Institute of Medical Research)Graham R. Bignell(Lund University)Niccolò Bolli(Oslo University Hospital)Åke Borg(Lund University)Anne‐Lise Børresen‐Dale(Oslo University Hospital)Sandrine Boyault(Wellcome Sanger Institute)Birgit Burkhardt(University of Cambridge)Adam P. Butler(Wellcome Sanger Institute)Carlos Caldas(Université Libre de Bruxelles)Helen Davies(German Cancer Research Center)Christine Desmedt(Université Libre de Bruxelles)Roland Eils(German Cancer Research Center)Jórunn E. Eyfjörd(Institute of Cancer Research)John A. Foekens(National Cancer Centre Japan)Mel Greaves(Institute of Cancer Research)Fumie Hosoda(Wellcome Sanger Institute)Barbara Hutter(Inserm)Tomislav Ilicic(Broad Institute)Sandrine Imbeaud(Délégation Paris 5)Marcin Imieliński(Broad Institute)Natalie Jäger(German Cancer Research Center)David Jones(German Cancer Research Center)David R. Jones(German Cancer Research Center)Stian Knappskog(The University of Queensland)Marcel Kool(Universidad de Oviedo)Sunil R. Lakhani(The University of Queensland)Carlos López-Otı́n(Harvard University)Sancha Martin(Wellcome Sanger Institute)Nikhil C. Munshi(Harvard University)Hiromi Nakamura(National Cancer Centre Japan)Paul A. Northcott(German Cancer Research Center)Marina Pajic(University of Glasgow)Elli Papaemmanuil(The University of Queensland)Angelo Paradiso(Universidad de Oviedo)John V. Pearson(The University of Queensland)Xosé S. Puente(Universidad de Oviedo)Keiran Raine(Wellcome Sanger Institute)Manasa Ramakrishna(Wellcome Sanger Institute)Andrea L. Richardson(Brigham and Women's Hospital)Julia Richter(German Cancer Research Center)Philip Rosenstiel(The Netherlands Cancer Institute)Matthias Schlesner(Radboud University Nijmegen)Ton N. Schumacher(Wellcome Sanger Institute)Paul N. Span(Radboud University Nijmegen)Jon W. Teague(King's College London)Yasushi Totoki(Universidad de Oviedo)Andrew Tutt(King's College London)Rafael Valdés‐Mas(Universidad de Oviedo)Marit M. van Buuren(Inserm)Laura van ‘t Veer(The University of Queensland)Anne Vincent‐Salomon(Inserm)Nicola Waddell(Délégation Paris 5)Lucy Yates(Wellcome Sanger Institute)Jessica Zucman‐Rossi(Délégation Paris 5)P. Andrew Futreal(German Cancer Research Center)Ultan McDermott(Broad Institute)Peter Lichter(The University of Queensland)Matthew Meyerson(Broad Institute)Sean M. Grimmond(The University of Queensland)Reiner Siebert(Christian-Albrechts-Universität zu Kiel)Elı́as Campo(German Cancer Research Center)Tatsuhiro Shibata(University of Cambridge)Stefan M. Pfister(German Cancer Research Center)Peter J. Campbell(University of Cambridge)Michael R. Stratton(Wellcome Sanger Institute)

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Cancer Genomics and Diagnostics DNA Repair Mechanisms Genetic factors in colorectal cancerCancerComputational biologyHuman genomeBiologyGeneticsGenomeGene

MeSH terms

AgingAlgorithmsCell Transformation, NeoplasticCytidine DeaminaseDNADNA Mutational AnalysisHumansModels, GeneticMutagensMutationNeoplasmsOrgan SpecificityTranscription, GeneticReproducibility of ResultsMutagenesis, Insertional