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Tumor-Residing Batf3 Dendritic Cells Are Required for Effector T Cell Trafficking and Adoptive T Cell Therapy

Cancer Cell · 2017 · Vol. 31(5) · pp. 711–723.e4
Stefani SprangerDaisy DaiBrendan HortonThomas F. Gajewski
CAR-T cell therapy researchImmunotherapy and Immune ResponsesCancer Immunotherapy and BiomarkersEffectorCell therapyT cellCancer researchImmunologyCell biologyMedicineBiologyImmune systemStem cell

MeSH terms

AnimalsChemotaxis, LeukocyteDendritic CellsGenotypeImmunologic MemoryMelanomaPhenotypeRepressor ProteinsSkin NeoplasmsT-LymphocytesTime FactorsSignal TransductionAntigens, CDImmunotherapy, AdoptiveMice, Knockout

Funding

  • Cancer Research Institute
  • Melanoma Research Foundation
  • University of Chicago
  • Jounce Therapeutics
  • National Cancer Institute
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