editorial Open AccessTop 1% cited
Two-sample Mendelian randomization: avoiding the downsides of a powerful, widely applicable but potentially fallible technique
International Journal of Epidemiology · 2016 · Vol. 45(6) · pp. 1717–1726
Fernando Pires Hartwig✉(University of Bristol)Neil M Davies(University of Bristol)Gibran Hemani(University of Bristol)George Davey Smith(Medical Research Council)
Abstract
[no abstract]
Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestockGenetic Mapping and Diversity in Plants and AnimalsMendelian randomizationRandomizationSample size determinationComputer scienceSample (material)MedicineStatisticsClinical trialMathematicsBiology
MeSH terms
HumansResearch DesignGuidelines as TopicMendelian Randomization Analysis
Funding
- University of Bristol
- Medical Research Council
- Economic and Social Research Council
Citations
919
FWCI
24.62
field-weighted impact
References
44
Percentile
100%
vs. same field & year
Citations per year
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References
Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology
Statistics in Medicine · 2007 · 4,904 citations
Genotype imputation for genome-wide association studies
Nature Reviews Genetics · 2010 · 1,718 citations
Mendelian randomization: prospects, potentials, and limitations
International Journal of Epidemiology · 2004 · 1,275 citations
Mendelian randomization: genetic anchors for causal inference in epidemiological studies
Human Molecular Genetics · 2014 · 4,933 citations
A global reference for human genetic variation
Nature · 2015 · 19,538 citations
‘Mendelian randomization’: can genetic epidemiology contribute to understanding environmental determinants of disease?*
International Journal of Epidemiology · 2003 · 6,297 citations
Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression
International Journal of Epidemiology · 2015 · 10,342 citations
Efficient Design for Mendelian Randomization Studies: Subsample and 2-Sample Instrumental Variable Estimators
American Journal of Epidemiology · 2013 · 1,464 citations
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