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The Oxford Nanopore MinION: delivery of nanopore sequencing to the genomics community

Genome biology · 2016 · Vol. 17(1) · pp. 239–239
Miten JainHugh E. OlsenBenedict PatenMark Akeson

Abstract

Nanopore DNA strand sequencing has emerged as a competitive, portable technology. Reads exceeding 150 kilobases have been achieved, as have in-field detection and analysis of clinical pathogens. We summarize key technical features of the Oxford Nanopore MinION, the dominant platform currently available. We then discuss pioneering applications executed by the genomics community.

Nanopore and Nanochannel Transport StudiesGenomics and Phylogenetic StudiesBacteriophages and microbial interactionsMinionNanopore sequencingNanoporeBiologyGenomicsDNA sequencingComputational biologyGenome BiologyGenomeGenetics

MeSH terms

AlgorithmsAneuploidyDNAHumansReproducibility of ResultsComputational BiologyGenomicsNanoporesHigh-Throughput Nucleotide Sequencing

Funding

  • National Institutes of Health
  • National Human Genome Research Institute
Citations
1,645
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References
The potential and challenges of nanopore sequencing
Nature Biotechnology · 2008 · 2,507 citations
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