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The feasibility and effect of deprescribing in older adults on mortality and health: a systematic review and meta‐analysis

British Journal of Clinical Pharmacology · 2016 · Vol. 82(3) · pp. 583–623
Amy PageRhonda CliffordKathleen N. PotterDarren C. SchwartzChristopher Etherton‐Beer

Abstract

Although nonrandomized data suggested that deprescribing reduces mortality, deprescribing was not shown to alter mortality in randomized studies. Mortality was significantly reduced when applying patient-specific interventions to deprescribe in randomized studies.

Pharmaceutical Practices and Patient OutcomesBlood Pressure and Hypertension StudiesHealth Systems, Economic Evaluations, Quality of LifeDeprescribingPolypharmacyMedicinePsychological interventionQuality of life (healthcare)Meta-analysisRandomized controlled trialAdverse effectBeers CriteriaEmergency medicine

MeSH terms

DeprescriptionsHumansPolypharmacyInappropriate Prescribing
Citations
492
FWCI
22.39
field-weighted impact
References
176
Percentile
100%
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