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Polypharmacy cutoff and outcomes: five or more medicines were used to identify community-dwelling older men at risk of different adverse outcomes

Journal of Clinical Epidemiology · 2012 · Vol. 65(9) · pp. 989–995
Danijela GnjidicSarah N. HilmerFiona BlythVasi NaganathanLouise M. WaiteMarkus J. SeibelAndrew J. McLachlanRobert G. CummingDavid J. HandelsmanDavid G. Le Couteur
Pharmaceutical Practices and Patient OutcomesHealth Systems, Economic Evaluations, Quality of LifeBlood Pressure and Hypertension StudiesPolypharmacyMedicineYouden's J statisticConfidence intervalOdds ratioReceiver operating characteristicCutoffAdverse effectGeriatricsGerontology

MeSH terms

Accidental FallsAgedAged, 80 and overCognition DisordersDisability EvaluationHumansMaleROC CurveGeriatric AssessmentOdds RatioSurvival AnalysisFrail ElderlyOutcome Assessment, Health CarePolypharmacyPrescription Drugs
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1,153
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20.36
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42
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References
The physical activity scale for the elderly (PASE): Development and evaluation
Journal of Clinical Epidemiology · 1993 · 3,147 citations
Polypharmacy and falls in the middle age and elderly population
British Journal of Clinical Pharmacology · 2005 · 416 citations
Vascular dementia
Neurology · 1993 · 4,887 citations
Clinical diagnosis of Alzheimer's disease
Neurology · 1984 · 27,910 citations
Frailty in Older Adults: Evidence for a Phenotype
The Journals of Gerontology Series A · 2001 · 23,899 citations
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