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Serum Immunoreactive-Leptin Concentrations in Normal-Weight and Obese Humans
New England Journal of Medicine · 1996 · Vol. 334(5) · pp. 292–295
Robert V. Considine✉Madhur K. SinhaMark L. Heiman(Eli Lilly (United States))Aidas Kriauciunas(Eli Lilly (United States))Thomas W. Stephens(Eli Lilly (United States))Mark R. NyceJoanna P. OhannesianCheryl MarcoLinda J. McKee(Cancer Research And Biostatistics)Thomas Bauer(Thomas Jefferson University)F. José
Abstract
Serum leptin concentrations are correlated with the percentage of body fat, suggesting that most obese persons are insensitive to endogenous leptin production.
Regulation of Appetite and ObesityBiochemical Analysis and Sensing TechniquesAdipokines, Inflammation, and Metabolic DiseasesLeptinEndocrinologyMedicineInternal medicineObesityHormoneGeneBody weightBiologyGenetics
MeSH terms
Adipose TissueAdultFemaleHumansMaleObesityProteinsRadioimmunoassayReference ValuesRegression AnalysisRNA, MessengerWeight LossGene ExpressionBody Mass IndexAdipocytes
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