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Analysis of the microbiome: Advantages of whole genome shotgun versus 16S amplicon sequencing

Biochemical and Biophysical Research Communications · 2015 · Vol. 469(4) · pp. 967–977
Ravi RanjanAsha RaniAhmed A. MetwallyHalvor S. McGeeDavid L. Perkins
Gut microbiota and healthProbiotics and Fermented FoodsClostridium difficile and Clostridium perfringens researchShotgun sequencingMicrobiomeAmpliconContigBiologyComputational biologyShotgunAmplicon sequencingMetagenomicsGenome

MeSH terms

BacteriaBase SequenceChromosome MappingDNA, BacterialHumansMolecular Sequence DataRNA, Ribosomal, 16SSensitivity and SpecificityReproducibility of ResultsSequence Analysis, DNAMetagenomeMicrobiota

Funding

  • University of Illinois at Chicago
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