article Open AccessTop 1% cited
An atlas of genetic correlations across human diseases and traits
Nature Genetics · 2015 · Vol. 47(11) · pp. 1236–1241
Brendan Bulik‐Sullivan✉(Broad Institute)Hilary K. Finucane✉(Massachusetts Institute of Technology)Verneri Anttila(Broad Institute)Alexander Gusev(Harvard University)Felix R. Day(University of Cambridge)Po‐Ru Loh(Broad Institute)Laramie E. Duncan(Broad Institute)John R. B. Perry(University of Cambridge)Nick Patterson(Broad Institute)Elise Robinson(Broad Institute)Mark J. Daly(Broad Institute)Alkes L. Price(Broad Institute)Benjamin M. Neale(Broad Institute)
Genetic Associations and EpidemiologyAutism Spectrum Disorder ResearchGenetics and Neurodevelopmental DisordersGenome-wide association studyBiologyGenetic correlationGenetic associationCorrelationTraitSingle-nucleotide polymorphismGeneticsEducational attainmentSample size determination
MeSH terms
AlgorithmsComputer SimulationDiseaseFemaleGenotypeHumansMaleModels, GeneticPhenotypeRegression AnalysisLinkage DisequilibriumGenetic Predisposition to DiseasePolymorphism, Single NucleotideQuantitative Trait LociGenome-Wide Association Study
Funding
- Medical Research Council
Citations
4,591
FWCI
214.91
field-weighted impact
References
65
Percentile
100%
vs. same field & year
Citations per year
Cited by
Collider scope: when selection bias can substantially influence observed associations
International Journal of Epidemiology · 2017 · 924 citations
Heart Disease and Stroke Statistics—2023 Update: A Report From the American Heart Association
Circulation · 2023 · 5,692 citations
Benefits and limitations of genome-wide association studies
Nature Reviews Genetics · 2019 · 2,137 citations
Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies
The Lancet Neurology · 2019 · 2,465 citations
Integrative approaches for large-scale transcriptome-wide association studies
Nature Genetics · 2016 · 2,654 citations
Tutorial: a guide to performing polygenic risk score analyses
Nature Protocols · 2020 · 1,959 citations
Meta-analysis of genome-wide association studies for height and body mass index in ∼700000 individuals of European ancestry
Human Molecular Genetics · 2018 · 2,483 citations
A cross-population atlas of genetic associations for 220 human phenotypes
Nature Genetics · 2021 · 2,289 citations
References
Partitioning heritability by functional annotation using genome-wide association summary statistics
Nature Genetics · 2015 · 2,993 citations
Improved Heritability Estimation from Genome-wide SNPs
The American Journal of Human Genetics · 2012 · 834 citations
Power and Predictive Accuracy of Polygenic Risk Scores
PLoS Genetics · 2013 · 1,622 citations
GCTA: A Tool for Genome-wide Complex Trait Analysis
The American Journal of Human Genetics · 2010 · 9,109 citations
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
Nature Genetics · 2013 · 2,335 citations
Mendelian randomization: genetic anchors for causal inference in epidemiological studies
Human Molecular Genetics · 2014 · 4,933 citations
‘Mendelian randomization’: can genetic epidemiology contribute to understanding environmental determinants of disease?*
International Journal of Epidemiology · 2003 · 6,297 citations
A meta-analysis of worldwide studies demonstrates an association between schizophrenia and tobacco smoking behaviors
Schizophrenia Research · 2005 · 1,273 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.
