article Open AccessTop 1% cited
Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas
Acta Neuropathologica · 2009 · Vol. 118(4) · pp. 469–474
Christian Hartmann✉(Heidelberg University)Jochen Meyer(Heidelberg University)Jörg Balß(German Cancer Research Center)David Capper(Heidelberg University)Wolf Mueller(Heidelberg University)Arne Christians(Heidelberg University)Jörg Felsberg(Heinrich Heine University Düsseldorf)Marietta Wolter(Heinrich Heine University Düsseldorf)Christian Mawrin(Otto-von-Guericke University Magdeburg)Wolfgang Wick(Heidelberg University)Michael Weller(University Hospital of Zurich)Christel Herold‐Mende(Heidelberg University)Andreas Unterberg(Heidelberg University)Judith W. M. Jeuken(Radboud University Nijmegen)Pieter Wesseling(Radboud University Nijmegen)Guido Reifenberger(Heinrich Heine University Düsseldorf)Andreas von Deimling(German Cancer Research Center)
Glioma Diagnosis and TreatmentVascular Malformations Diagnosis and TreatmentMeningioma and schwannoma managementIDH2IDH1Isocitrate dehydrogenaseAnaplastic astrocytomaMutationAstrocytomaBiologyOligodendroglial TumorOligodendrogliomaCancer research
MeSH terms
AdultAge FactorsBrainBrain NeoplasmsCell DifferentiationDNA Mutational AnalysisFemaleGliomaHumansIsocitrate DehydrogenaseMaleMiddle AgedMutationPrognosisTumor Cells, Cultured
Citations
1,148
FWCI
36.96
field-weighted impact
References
23
Percentile
100%
vs. same field & year
Citations per year
Cited by
Frequent <i>ATRX</i> , <i>CIC</i> , <i>FUBP1</i> and <i>IDH1</i> mutations refine the classification of malignant gliomas
Oncotarget · 2012 · 577 citations
Identification of a CpG Island Methylator Phenotype that Defines a Distinct Subgroup of Glioma
Cancer Cell · 2010 · 2,346 citations
Glioblastoma: pathology, molecular mechanisms and markers
Acta Neuropathologica · 2015 · 710 citations
Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: implications for classification of gliomas
Acta Neuropathologica · 2010 · 840 citations
Novel mutations and their functional and clinical relevance in myeloproliferative neoplasms: JAK2, MPL, TET2, ASXL1, CBL, IDH and IKZF1
Leukemia · 2010 · 521 citations
The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate
Cancer Cell · 2010 · 1,966 citations
Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation
Cancer Cell · 2010 · 2,713 citations
References
The 2007 WHO Classification of Tumours of the Central Nervous System
Acta Neuropathologica · 2007 · 4,566 citations
IDH1 Mutations Are Early Events in the Development of Astrocytomas and Oligodendrogliomas
American Journal Of Pathology · 2009 · 1,020 citations
Analysis of the IDH1 codon 132 mutation in brain tumors
Acta Neuropathologica · 2008 · 1,034 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.