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Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade

The Lancet Neurology · 2009 · Vol. 9(1) · pp. 119–128
Clifford R. JackDavid S. KnopmanWilliam J. JagustLeslie M. ShawPaul AisenMichael W. WeinerRonald C. PetersenJohn Q. Trojanowski
Alzheimer's disease research and treatmentsDementia and Cognitive Impairment ResearchAdvanced Neuroimaging Techniques and ApplicationsNeurodegenerationPathologicalMedicineNeuroscienceAmyloid (mycology)DiseaseAtrophyBiomarkerPathologyDementia

MeSH terms

AgingAlzheimer DiseaseBrainCognition DisordersHumansMagnetic Resonance ImagingModels, NeurologicalTime FactorsSignal TransductionBiomarkersAmyloid beta-Peptidestau ProteinsDisease ProgressionPositron-Emission TomographyApolipoprotein E4

Funding

  • Bristol-Myers Squibb
  • National Institutes of Health
  • National Institute on Aging
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