reviewTop 1% cited
The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics
Nature Reviews Drug Discovery · 2011 · Vol. 10(9) · pp. 698–712
Eric Karran✉(Janssen (Belgium))Marc Mercken(Janssen (Belgium))Bart De Strooper(Vlaams Instituut voor Biotechnologie)
Alzheimer's disease research and treatmentsComputational Drug Discovery MethodsCholinesterase and Neurodegenerative DiseasesDiseaseAmyloid (mycology)Amyloid βBiochemistry of Alzheimer's diseaseMedicineNeuroscienceDrug developmentClinical trialβ amyloidAlzheimer's disease
MeSH terms
Alzheimer DiseaseAnimalsBrain ChemistryHumansResearch DesignAmyloid beta-PeptidesTreatment FailureClinical Trials, Phase II as TopicClinical Trials, Phase III as TopicAge of OnsetDisease ProgressionPlaque, Amyloid
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