article Open AccessTop 1% cited
Decreased gut microbiota diversity, delayed Bacteroidetes colonisation and reduced Th1 responses in infants delivered by Caesarean section
Gut · 2013 · Vol. 63(4) · pp. 559–566
Hedvig E. Jakobsson(Karolinska Institutet)Thomas Abrahamsson(Linköping University)Maria C. Jenmalm(Linköping University)Keith Harris(University of Glasgow)Christopher Quince(University of Glasgow)Cecilia Jernberg(Swedish Institute)Bengt Björkstén(Örebro University)Lars Engstrand(Karolinska Institutet)Anders F. Andersson✉(Science for Life Laboratory)
Abstract
CS was associated with a lower total microbial diversity, delayed colonisation of the Bacteroidetes phylum and reduced Th1 responses during the first 2 years of life.
Pediatric health and respiratory diseasesAsthma and respiratory diseasesGut microbiota and healthBacteroidetesColonisationBiologyMicrobiomeCaesarean sectionPyrosequencingImmunologyMicrobiologyColonizationPregnancy
MeSH terms
Age FactorsCesarean SectionDNA, BacterialFecesFemaleHumansImmunity, CellularInfantInfant, NewbornIntestinesMaleRNA, Ribosomal, 16STh1 CellsBacteroidetesChemokine CXCL10
Funding
- Engineering and Physical Sciences Research Council
Citations
976
FWCI
94.20
field-weighted impact
References
56
Percentile
100%
vs. same field & year
Citations per year
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References
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PLoS Biology · 2007 · 2,829 citations
Low diversity of the gut microbiota in infants with atopic eczema
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