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Interleukin-2 Signaling via STAT5 Constrains T Helper 17 Cell Generation
Immunity · 2007 · Vol. 26(3) · pp. 371–381
Arian Laurence(National Institutes of Health)Cristina M. Tato✉(National Institute of Arthritis and Musculoskeletal and Skin Diseases)Todd S. Davidson(National Institute of Allergy and Infectious Diseases)Yuka Kanno(National Institute of Arthritis and Musculoskeletal and Skin Diseases)Zhi Chen(National Institutes of Health)Zhengju Yao(National Institute of Arthritis and Musculoskeletal and Skin Diseases)Rebecca B. Blank(National Institutes of Health)Françoise Meylan(National Institute of Arthritis and Musculoskeletal and Skin Diseases)Richard M. Siegel(National Institutes of Health)Lothar Hennighausen(National Institute of Diabetes and Digestive and Kidney Diseases)Ethan M. Shevach(National Institute of Allergy and Infectious Diseases)John J. O’Shea(National Institute of Arthritis and Musculoskeletal and Skin Diseases)
Psoriasis: Treatment and PathogenesisT-cell and B-cell ImmunologyImmune Cell Function and InteractionBiologySTAT5EffectorCell biologySTAT3Transcription factorInterleukin 17T cellImmunologyRegulator
MeSH terms
AnimalsCell DifferentiationT-Lymphocytes, Helper-InducerInterleukin-2Lymphocyte ActivationMice, Mutant StrainsApoptosisInterleukin-17STAT3 Transcription FactorSTAT5 Transcription FactorMice
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1,469
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References
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
The Journal of Experimental Medicine · 2005 · 4,029 citations
The lifestyle of naturally occurring CD4<sup>+</sup>CD25<sup>+</sup>Foxp3<sup>+</sup> regulatory T cells
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CD4+CD25+ Immunoregulatory T Cells Suppress Polyclonal T Cell Activation In Vitro by Inhibiting Interleukin 2 Production
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Interleukin 17–producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
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TGFβ in the Context of an Inflammatory Cytokine Milieu Supports De Novo Differentiation of IL-17-Producing T Cells
Immunity · 2006 · 3,566 citations
Divergent Pro- and Antiinflammatory Roles for IL-23 and IL-12 in Joint Autoimmune Inflammation
The Journal of Experimental Medicine · 2003 · 1,633 citations
The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells
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