articleTop 10% cited
Physiologically Based Pharmacokinetic Modeling 1: Predicting the Tissue Distribution of Moderate-to-Strong Bases
Journal of Pharmaceutical Sciences · 2005 · Vol. 94(6) · pp. 1259–1276
Drug Transport and Resistance MechanismsPharmacogenetics and Drug MetabolismRenal function and acid-base balancePharmacokineticsAdipose tissueChemistryPredictabilityDrugDistribution (mathematics)PharmacologyBiochemistryMedicinePhysics
MeSH terms
AnimalsBlood ProteinsBrainModels, BiologicalPharmacokineticsProtein BindingTissue DistributionRats
Funding
- University of Manchester
- Biotechnology and Biological Sciences Research Council
Citations
771
FWCI
6.82
field-weighted impact
References
59
Percentile
98%
vs. same field & year
Citations per year
Cited by
Physiologically based pharmacokinetic modelling 2: Predicting the tissue distribution of acids, very weak bases, neutrals and zwitterions
Journal of Pharmaceutical Sciences · 2006 · 931 citations
Applications of Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulation During Regulatory Review
Clinical Pharmacology & Therapeutics · 2010 · 511 citations
References
Physiological Parameters in Laboratory Animals and Humans
Pharmaceutical Research · 1993 · 2,894 citations
Prediction of Pharmacokinetics Prior to In Vivo Studies. 1. Mechanism‐Based Prediction of Volume of Distribution
Journal of Pharmaceutical Sciences · 2002 · 558 citations
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