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Review article: insights into colonic protein fermentation, its modulation and potential health implications

Alimentary Pharmacology & Therapeutics · 2015 · Vol. 43(2) · pp. 181–196
Chu K YaoJane G. MuirPeter G. Gibson

Abstract

The direct clinical relevance of excessive protein fermentation in the pathogenesis of irritable bowel syndrome, malodorous flatus and ulcerative colitis are underexplored. Manipulating dietary carbohydrate and protein intake have potential therapeutic applications in such settings and warrant further clinical studies.

Digestive system and related healthGut microbiota and healthProbiotics and Fermented FoodsFermentationResistant starchIrritable bowel syndromeMedicineMicrobiomeUlcerative colitisFood scienceBiochemistryChemistryGastroenterology

MeSH terms

AmmoniaColonDietDietary CarbohydratesDietary ProteinsFatty Acids, VolatileFermentationHumansColorectal Neoplasms

Funding

  • Pfizer
  • AbbVie
  • Takeda Pharmaceuticals U.S.A.
  • Danone
  • Ferring
Citations
419
FWCI
13.59
field-weighted impact
References
147
Percentile
99%
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