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Validation and validity of diagnoses in the General Practice Research Database: a systematic review

British Journal of Clinical Pharmacology · 2009 · Vol. 69(1) · pp. 4–14
Emily HerrettSara L. ThomasW. Marieke SchoonenLiam SmeethAndrew J. Hall

Abstract

A number of methods have been used to assess validity. Overall, estimates of validity were high. However, the quality of reporting of the validations was often inadequate to permit a clear interpretation. Not all methods provided a quantitative estimate of validity and most methods considered only the positive predictive value of a set of diagnostic codes in a highly selected group of cases. We make recommendations for methodology and reporting to strengthen further the use of the GPRD in research.

Meta-analysis and systematic reviewsHealth Systems, Economic Evaluations, Quality of LifePrimary Care and Health OutcomesMedical diagnosisMedicineSystematic reviewMEDLINEDatabaseComputer scienceMedical physicsPathology

MeSH terms

AlgorithmsClinical CompetenceDiagnostic ErrorsFamily PracticeHumansSurveys and QuestionnairesResearchReproducibility of ResultsDatabases, Factual
Citations
1,107
FWCI
31.93
field-weighted impact
References
29
Percentile
100%
vs. same field & year
Citations per year
References
Epidemiology of fractures in England and Wales
Bone · 2001 · 1,128 citations
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