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Cause-specific mortality in patients with severe psoriasis: a population-based cohort study in the U.K.

British Journal of Dermatology · 2010 · Vol. 163(3) · pp. 586–592
Katrina AbuabaraRahat S. AzfarDaniel B. ShinAndrea L. NeimannAndrea B. TroxelJoel M. Gelfand

Abstract

Severe psoriasis is associated with an increased risk of death from a variety of causes, with cardiovascular death being the most common aetiology. These patients were also at increased risk of death from causes not previously reported, such as infection, kidney disease and dementia. Additional studies are necessary to determine the degree to which excess causes of death are due to psoriasis, its treatments, associated behaviours, or other factors.

Psoriasis: Treatment and PathogenesisDermatology and Skin DiseasesHealth Systems, Economic Evaluations, Quality of LifeBiostatisticsEpidemiologyMedicinePopulationRetrospective cohort studyCohortLibrary scienceFamily medicineSurgeryPathology

MeSH terms

Risk FactorsCohort StudiesProportional Hazards ModelsAdultAgedCardiovascular DiseasesCause of DeathFemaleUnited KingdomHumansMaleMiddle AgedPsoriasisAge Distribution
Citations
464
FWCI
8.48
field-weighted impact
References
68
Percentile
98%
vs. same field & year
Citations per year
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References
The Risk of Mortality in Patients With Psoriasis
Archives of Dermatology · 2007 · 525 citations
Prevalence of cardiovascular risk factors in patients with psoriasis
Journal of the American Academy of Dermatology · 2006 · 1,003 citations
Psoriasis: epidemiology, clinical features, and quality of life
Annals of the Rheumatic Diseases · 2005 · 1,094 citations
Validation and validity of diagnoses in the General Practice Research Database: a systematic review
British Journal of Clinical Pharmacology · 2009 · 1,107 citations
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Cause-specific mortality in patients with severe psoriasis: a population-based cohort study in the U.K. · Scinovex