article Open AccessTop 1% cited
The microglial sensome revealed by direct RNA sequencing
Nature Neuroscience · 2013 · Vol. 16(12) · pp. 1896–1905
Suzanne E. Hickman✉(Massachusetts General Hospital)Nathan D. Kingery(Massachusetts General Hospital)Toshiro K. Ohsumi(Massachusetts General Hospital)Mark L. Borowsky(Massachusetts General Hospital)Li-chong Wang(Advanced Cell Diagnostics (United States))Terry K. Means(Massachusetts General Hospital)Joseph El Khoury✉(Massachusetts General Hospital)
Neuroinflammation and Neurodegeneration MechanismsImmune cells in cancerAlzheimer's disease research and treatmentsMicrogliaBiologyNeuroprotectionTranscriptomeRNAEndogenyGene expressionPriming (agriculture)Cell biologyGene
MeSH terms
Age FactorsAnimalsFlow CytometryLigandsMice, Inbred C57BLMass SpectrometrySequence Analysis, RNALeukocyte Common AntigensMicrogliaMacrophages, PeritonealComputational BiologyCD11b AntigenMiceTranscriptome
Citations
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References
Quantitative Monitoring of Gene Expression Patterns with a Complementary DNA Microarray
Science · 1995 · 9,572 citations
Transformation from a neuroprotective to a neurotoxic microglial phenotype in a mouse model of ALS
Experimental Neurology · 2012 · 417 citations
Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain
Neuroscience · 1990 · 2,020 citations
Microglia-mediated neurotoxicity: uncovering the molecular mechanisms
Nature reviews. Neuroscience · 2006 · 4,065 citations
RNA sequencing: advances, challenges and opportunities
Nature Reviews Genetics · 2010 · 2,169 citations
Alternative Activation of Macrophages: Mechanism and Functions
Immunity · 2010 · 4,114 citations
Physiology of Microglia
Physiological Reviews · 2011 · 3,469 citations
Molecular Classification of Cancer: Class Discovery and Class Prediction by Gene Expression Monitoring
Science · 1999 · 11,587 citations
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