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Transformation from a neuroprotective to a neurotoxic microglial phenotype in a mouse model of ALS

Experimental Neurology · 2012 · Vol. 237(1) · pp. 147–152
Bing LiaoWeihua ZhaoDavid R. BeersJenny S. HenkelStanley H. Appel
Amyotrophic Lateral Sclerosis ResearchNeuroinflammation and Neurodegeneration MechanismsNeurogenetic and Muscular Disorders ResearchMicrogliaNeuroprotectionNeuroinflammationAmyotrophic lateral sclerosisNeuroscienceBiologyGenetically modified mouseNeurodegenerationImmunologyTransgene

MeSH terms

Amyotrophic Lateral SclerosisAnimalsAstrocytesCells, CulturedDisease Models, AnimalHumansInflammationMice, Inbred C57BLMice, Neurologic MutantsMice, TransgenicMotor NeuronsPhenotypeSuperoxide DismutaseTransformation, GeneticMicroglia
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417
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Transformation from a neuroprotective to a neurotoxic microglial phenotype in a mouse model of ALS · Scinovex