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β-catenin directly displaces Groucho/TLE repressors from Tcf/Lef in Wnt-mediated transcription activation

Nature Structural & Molecular Biology · 2005 · Vol. 12(4) · pp. 364–371
Danette L. DanielsWilliam I. Weis
Wnt/β-catenin signaling in development and cancerCancer-related gene regulationKruppel-like factors researchWnt signaling pathwayRepressorTranscription factorCoactivatorCell biologyCell fate determinationPsychological repressionCateninDNA-binding proteinTranscription (linguistics)

MeSH terms

AnimalsCytoskeletal ProteinsDNADNA-Binding ProteinsHumansPeptide FragmentsProtein BindingRepressor ProteinsTranscription FactorsTranscriptional ActivationTrans-ActivatorsIntercellular Signaling Peptides and ProteinsWnt Proteinsbeta CateninMice

Funding

  • National Institutes of Health
  • School of Medicine, Stanford University
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541
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References
CBP/p300 in cell growth, transformation, and development
Genes & Development · 2000 · 1,757 citations
Wnt signaling: a common theme in animal development
Genes & Development · 1997 · 2,571 citations
β-catenin is a target for the ubiquitin–proteasome pathway
The EMBO Journal · 1997 · 2,503 citations
Wnt signaling and cancer
Genes & Development · 2000 · 3,172 citations
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