article Open AccessTop 10% cited
Analysis of induced sputum in adults with asthma: identification of subgroup with isolated sputum neutrophilia and poor response to inhaled corticosteroids
Thorax · 2002 · Vol. 57(10) · pp. 875–879
R H Green✉(Glenfield Hospital)
Abstract
These results suggest the presence of a distinct subgroup of patients with mild to moderate asthma who have predominantly neutrophilic airway inflammation and who respond less well to treatment with inhaled corticosteroids.
Asthma and respiratory diseasesChronic Obstructive Pulmonary Disease (COPD) ResearchRespiratory and Cough-Related ResearchMedicineSputumNeutrophiliaAsthmaEosinophilInternal medicineMethacholineBudesonideGastroenterologyExacerbation
MeSH terms
Administration, InhalationAdministration, TopicalAdultAnti-Inflammatory AgentsAsthmaEosinophiliaFemaleForced Expiratory VolumeGlucocorticoidsHumansInflammationLeukocytosisMaleSputumVital Capacity
Citations
845
FWCI
6.87
field-weighted impact
References
32
Percentile
98%
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Citations per year
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References
Evidence That Severe Asthma Can Be Divided Pathologically into Two Inflammatory Subtypes with Distinct Physiologic and Clinical Characteristics
American Journal of Respiratory and Critical Care Medicine · 1999 · 1,226 citations
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