reviewTop 1% cited
Asthma phenotypes: the evolution from clinical to molecular approaches
Nature Medicine · 2012 · Vol. 18(5) · pp. 716–725
Sally E. Wenzel✉(UPMC Health System)
Asthma and respiratory diseasesIL-33, ST2, and ILC PathwaysHelicobacter pylori-related gastroenterology studiesPhenotypeAsthmaGenetic heterogeneityClinical phenotypePrecision medicineDiseaseComputational biologyMedicineBioinformaticsBiology
MeSH terms
AnimalsAsthmaAsthma, Exercise-InducedHumansObesityPhenotypeBiomarkersTh2 Cells
Citations
2,354
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74.88
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References
The anti-IgE antibody omalizumab reduces exacerbations and steroid requirement in allergic asthmatics
European Respiratory Journal · 2001 · 826 citations
Evidence That Severe Asthma Can Be Divided Pathologically into Two Inflammatory Subtypes with Distinct Physiologic and Clinical Characteristics
American Journal of Respiratory and Critical Care Medicine · 1999 · 1,226 citations
T-helper Type 2–driven Inflammation Defines Major Subphenotypes of Asthma
American Journal of Respiratory and Critical Care Medicine · 2009 · 1,796 citations
Asthma endotypes: A new approach to classification of disease entities within the asthma syndrome
Journal of Allergy and Clinical Immunology · 2011 · 1,140 citations
Cluster Analysis and Clinical Asthma Phenotypes
American Journal of Respiratory and Critical Care Medicine · 2008 · 1,981 citations
Omalizumab, anti-IgE recombinant humanized monoclonal antibody, for the treatment of severe allergic asthma
Journal of Allergy and Clinical Immunology · 2001 · 1,287 citations
An Official ATS Clinical Practice Guideline: Interpretation of Exhaled Nitric Oxide Levels (F <scp>e</scp> NO) for Clinical Applications
American Journal of Respiratory and Critical Care Medicine · 2011 · 2,433 citations
Leptin regulates proinflammatory immune responses
The FASEB Journal · 1998 · 1,172 citations
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