articleTop 1% cited
Early lactate clearance is associated with improved outcome in severe sepsis and septic shock*
Critical Care Medicine · 2004 · Vol. 32(8) · pp. 1637–1642
H. Bryant Nguyen✉(Loma Linda University)Emanuel P. RiversBernhard KnoblichGordon JacobsenAlexandria MuzzinJulie A. ResslerMichael C. Tomlanovich
Abstract
Lactate clearance early in the hospital course may indicate a resolution of global tissue hypoxia and is associated with decreased mortality rate. Patients with higher lactate clearance after 6 hrs of emergency department intervention have improved outcome compared with those with lower lactate clearance.
Sepsis Diagnosis and TreatmentHemodynamic Monitoring and TherapyClinical Reasoning and Diagnostic SkillsMedicineEmergency departmentSeptic shockIntensive care unitAPACHE IIIntensive careSepsisResuscitationEmergency medicineSAPS II
MeSH terms
Emergency Medical ServicesFemaleHumansLength of StayMaleMichiganMiddle AgedMultiple Organ FailureProspective StudiesShock, SepticCohort StudiesBiomarkersMultivariate AnalysisSurvival AnalysisHospital Mortality
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