articleTop 1% cited
Serum lactate is associated with mortality in severe sepsis independent of organ failure and shock*
Critical Care Medicine · 2009 · Vol. 37(5) · pp. 1670–1677
Mark E. Mikkelsen✉(University of Pennsylvania)Andrea MiltiadesDavid F. GaieskiMunish GoyalBarry D. FuchsChirag V. ShahScarlett L. BellamyJason D. Christie
Abstract
Initial serum lactate was associated with mortality independent of clinically apparent organ dysfunction and shock in patients admitted to the ED with severe sepsis. Both intermediate and high serum lactate levels were independently associated with mortality.
Sepsis Diagnosis and TreatmentHemodynamic Monitoring and TherapyClinical Reasoning and Diagnostic SkillsMedicineSepsisInternal medicineShock (circulatory)Septic shockOdds ratioOrgan dysfunctionConfoundingGastroenterologyMultiple organ dysfunction syndrome
MeSH terms
Academic Medical CentersAdolescentAdultAge FactorsAgedAged, 80 and overCause of DeathCritical CareEmergency Service, HospitalFemaleHumansLactatesMaleMiddle AgedMultiple Organ Failure
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1,012
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