article Open AccessTop 1% cited
Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic Shock
New England Journal of Medicine · 2001 · Vol. 345(19) · pp. 1368–1377
Emanuel P. Rivers✉(Henry Ford Health System)Bryant NguyenSuzanne HavstadJulie A. ResslerAlexandria MuzzinBernhard KnoblichKevin R. WardMichael Tomlanovich
Abstract
Early goal-directed therapy provides significant benefits with respect to outcome in patients with severe sepsis and septic shock.
Sepsis Diagnosis and TreatmentHemodynamic Monitoring and TherapyCardiac Arrest and ResuscitationMedicineEarly goal-directed therapySeptic shockPreloadIntensive care medicineAfterloadSepsisIntensive care unitShock (circulatory)Contractility
MeSH terms
AgedAlgorithmsBlood PressureCardiovascular AgentsEmergency Service, HospitalFemaleFluid TherapyHealth ResourcesHemodynamicsHospitals, UrbanHumansMaleMiddle AgedMonitoring, PhysiologicOxygen
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