article Open AccessTop 10% cited
Butyrate Enhances the Intestinal Barrier by Facilitating Tight Junction Assembly via Activation of AMP-Activated Protein Kinase in Caco-2 Cell Monolayers
Journal of Nutrition · 2009 · Vol. 139(9) · pp. 1619–1625
Luying Peng(Tongji University)Zhongrong Li(Wenzhou Medical University)Robert S. Green(Icahn School of Medicine at Mount Sinai)Ian R. Holzmanr(Icahn School of Medicine at Mount Sinai)Jing Lin✉(Icahn School of Medicine at Mount Sinai)
Barrier Structure and Function StudiesMetabolism, Diabetes, and CancerBiochemical Analysis and Sensing TechniquesButyrateTight junctionAMPKCell biologySodium butyrateCaco-2Protein kinase AChemistryIntracellularCell junction
MeSH terms
ButyratesEpitheliumHumansIntestinal MucosaInulinMembrane ProteinsPermeabilityPhosphorylationUp-RegulationElectric ImpedanceCaco-2 CellsTight JunctionsProtein Kinase InhibitorsAMP-Activated Protein Kinases
Citations
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References
49
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99%
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References
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Effects of Butyrate on Intestinal Barrier Function in a Caco-2 Cell Monolayer Model of Intestinal Barrier
Pediatric Research · 2007 · 486 citations
Stimulatory effect of short-chain fatty acids on epithelial cell proliferation in the rat intestine: a possible explanation for trophic effects of fermentable fibre, gut microbes and luminal trophic factors
British Journal Of Nutrition · 1987 · 654 citations
5-Aminoimidazole-4-Carboxamide Ribonucleoside. A Specific Method for Activating AMP-Activated Protein Kinase in Intact Cells?
European Journal of Biochemistry · 1995 · 1,182 citations
Calmodulin-dependent protein kinase kinase-β is an alternative upstream kinase for AMP-activated protein kinase
Cell Metabolism · 2005 · 1,557 citations
Ca2+/calmodulin-dependent protein kinase kinase-β acts upstream of AMP-activated protein kinase in mammalian cells
Cell Metabolism · 2005 · 1,371 citations
5-Aminoimidazole-4-Carboxamide Ribonucleoside. A Specific Method for Activating AMP-Activated Protein Kinase in Intact Cells?
European Journal of Biochemistry · 1995 · 909 citations
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