review Open AccessTop 1% cited
AMP-activated protein kinase: Ancient energy gauge provides clues to modern understanding of metabolism
Cell Metabolism · 2005 · Vol. 1(1) · pp. 15–25
Barbara B. Kahn✉(Beth Israel Deaconess Medical Center)Thierry Alquier(Beth Israel Deaconess Medical Center)David Carling(Hammersmith Hospital)D. Grahame Hardie(University of Dundee)
Metabolism, Diabetes, and CancerPancreatic function and diabetesDiet, Metabolism, and DiseaseEnergy metabolismProtein kinase AKinaseCell biologyComputational biologyBiologyEndocrinology
MeSH terms
AnimalsBody WeightDisease Models, AnimalHomeostasisHormones, EctopicHumansInsulinModels, BiologicalMultienzyme ComplexesMutationPhysical Conditioning, AnimalSignal TransductionExerciseProtein Serine-Threonine KinasesAdaptor Proteins, Signal Transducing
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References
Management of cellular energy by the AMP‐activated protein kinase system
FEBS Letters · 2003 · 855 citations
LKB1 Is the Upstream Kinase in the AMP-Activated Protein Kinase Cascade
Current Biology · 2003 · 1,631 citations
Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase
Nature Medicine · 2002 · 4,196 citations
Adipose Tissue as an Endocrine Organ
The Journal of Clinical Endocrinology & Metabolism · 2004 · 5,411 citations
Upstream and downstream of mTOR
Genes & Development · 2004 · 4,184 citations
The AMP-activated protein kinase pathway – new players upstream and downstream
Journal of Cell Science · 2004 · 1,135 citations
AICA riboside increases AMP-activated protein kinase, fatty acid oxidation, and glucose uptake in rat muscle
American Journal of Physiology-Endocrinology and Metabolism · 1997 · 1,019 citations
Role of AMP-activated protein kinase in mechanism of metformin action
Journal of Clinical Investigation · 2001 · 5,364 citations
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