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Trial Design and Reporting Standards for Intra-Arterial Cerebral Thrombolysis for Acute Ischemic Stroke

Stroke · 2003 · Vol. 34(8) · pp. e109–37
Randall T. HigashidaAnthony J. Furlan

Abstract

In summary, this article serves to provide a more uniform set of criteria for clinical trials and reporting outcomes used in designing stroke trials involving intra-arterial thrombolytic agents, either alone or in combination with other therapies. It is anticipated that by having a more uniform set of reporting standards, more meaningful analysis of the data and the literature will be able to be achieved.

Acute Ischemic Stroke ManagementStroke Rehabilitation and RecoveryCerebrovascular and Carotid Artery DiseasesMedicineThrombolysisStroke (engine)Clinical trialTissue plasminogen activatorIntensive care medicineRandomized controlled trialFibrinolytic agentEmergency medicineInternal medicine

MeSH terms

Acute DiseaseBrain IschemiaClinical Trials as TopicFibrinolytic AgentsHumansInjections, Intra-ArterialMagnetic Resonance ImagingTerminology as TopicResearch DesignTechnology Assessment, BiomedicalTime FactorsTomography, X-Ray ComputedUnited StatesMulticenter Studies as TopicThrombolytic Therapy
Citations
1,508
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10.64
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120
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References
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Stroke · 1999 · 1,176 citations
Tissue Plasminogen Activator for Acute Ischemic Stroke
New England Journal of Medicine · 1995 · 11,620 citations
Functional evaluation : Barthel index
Medical Entomology and Zoology · 1965 · 12,854 citations
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Journal of the American Statistical Association · 1986 · 21,013 citations
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