reviewTop 1% cited

In search of a depressed mouse: utility of models for studying depression-related behavior in genetically modified mice

Molecular Psychiatry · 2004 · Vol. 9(4) · pp. 326–357

John F. Cryan✉(Novartis (Switzerland))Cédric Mombereau(Novartis (Switzerland))

Neurotransmitter Receptor Influence on Behavior Adipose Tissue and Metabolism Neuroendocrine regulation and behaviorAnhedoniaEndophenotypeLearned helplessnessPsychologyAntidepressantDepression (economics)Animal models of depressionPreclinical researchNeuroscienceTail suspension test

MeSH terms

AnimalsBehavior, AnimalDepressive DisorderDisease Models, AnimalMice, Mutant StrainsSensitivity and SpecificityReproducibility of ResultsAnimals, Genetically ModifiedMice

Citations

604

FWCI

9.90

field-weighted impact

References

428

Percentile

99%

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References

Behavioural despair in rats: A new model sensitive to antidepressant treatments

European Journal of Pharmacology · 1978 · 3,115 citations

Validity, reliability and utility of the chronic mild stress model of depression: a 10-year review and evaluation

Psychopharmacology · 1997 · 1,809 citations

Is the forced swimming test a suitable model for revealing antidepressant activity?

Psychopharmacology · 1988 · 1,047 citations

Increased hippocampal bdnf immunoreactivity in subjects treated with antidepressant medication

Biological Psychiatry · 2001 · 1,147 citations

Decreased serum brain-derived neurotrophic factor levels in major depressed patients

Psychiatry Research · 2002 · 1,216 citations

The tail suspension test: A new method for screening antidepressants in mice

Psychopharmacology · 1985 · 3,472 citations

Relationships between interleukin-6 activity, acute phase proteins, and function of the hypothalamic-pituitary-adrenal axis in severe depression

Psychiatry Research · 1993 · 442 citations

Chronic mild stress-induced anhedonia: A realistic animal model of depression

Neuroscience & Biobehavioral Reviews · 1992 · 1,147 citations

Chronic mild stress-induced anhedonia: A realistic animal model of depression

Neuroscience & Biobehavioral Reviews · 1992 · 1,147 citations

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