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Responsive cortical stimulation for the treatment of medically intractable partial epilepsy

Neurology · 2011 · Vol. 77(13) · pp. 1295–1304

Martha J. Morrell✉(NeuroPace (United States))

Abstract

This study provides Class I evidence that responsive cortical stimulation is effective in significantly reducing seizure frequency for 12 weeks in adults who have failed 2 or more antiepileptic medication trials, 3 or more seizures per month, and 1 or 2 seizure foci.

Neurological disorders and treatments Epilepsy research and treatment Neuroscience and Neuropharmacology ResearchIntractable epilepsyEpilepsyNeuroscienceStimulationPartial epilepsyMedicineBrain stimulationpartial seizuresCortical neuronsPsychology

MeSH terms

AdolescentAdultAgedAnticonvulsantsCerebral CortexCognition DisordersDisability EvaluationDouble-Blind MethodElectric Stimulation TherapyEpilepsies, PartialFemaleHumansMaleMiddle AgedNeuropsychological Tests

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Two‐year seizure reduction in adults with medically intractable partial onset epilepsy treated with responsive neurostimulation: Final results of the RNS System Pivotal trial