articleTop 1% cited
Development, cytokine profile and function of human interleukin 17–producing helper T cells
Nature Immunology · 2007 · Vol. 8(9) · pp. 950–957
Nicholas J. Wilson✉Katia BonifaceJason R. ChanBrent S. McKenzieWendy M. BlumenscheinJeanine MattsonBeth BashamKathleen M. SmithTaiying ChenFranck Morel(Université de Poitiers)Jean‐Claude Lecron(Centre Hospitalier Universitaire de Poitiers)Robert A. KasteleinJ. DanielTerrill K. McClanahanEdward P. BowmanRené de Waal Malefyt
Psoriasis: Treatment and PathogenesisDermatology and Skin DiseasesT-cell and B-cell ImmunologyCCL20BiologyImmunologyInterleukin 17Cell biologyInterleukin 23ChemokineCytokineInterleukin 22Interleukin
MeSH terms
Cell DifferentiationCells, CulturedEnzyme-Linked Immunosorbent AssayEpithelial CellsFlow CytometryT-Lymphocytes, Helper-InducerHumansImmunohistochemistryPsoriasisPolymerase Chain ReactionT-Lymphocyte SubsetsCytokinesInterleukin-17Antimicrobial Cationic PeptidesInterleukin-23
Funding
- National Health and Medical Research Council
- National Medical Research Council
Citations
2,001
FWCI
63.63
field-weighted impact
References
52
Percentile
100%
vs. same field & year
Citations per year
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References
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
Nature Immunology · 2005 · 4,203 citations
IL‐22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis
European Journal of Immunology · 2006 · 908 citations
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
The Journal of Experimental Medicine · 2005 · 4,029 citations
Novel p19 Protein Engages IL-12p40 to Form a Cytokine, IL-23, with Biological Activities Similar as Well as Distinct from IL-12
Immunity · 2000 · 2,788 citations
TH-17 cells in the circle of immunity and autoimmunity
Nature Immunology · 2007 · 1,510 citations
Interleukin 17–producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
Nature Immunology · 2005 · 4,662 citations
A Large-Scale Genetic Association Study Confirms IL12B and Leads to the Identification of IL23R as Psoriasis-Risk Genes
The American Journal of Human Genetics · 2007 · 1,080 citations
TGFβ in the Context of an Inflammatory Cytokine Milieu Supports De Novo Differentiation of IL-17-Producing T Cells
Immunity · 2006 · 3,566 citations
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