articleTop 1% cited
Plasma Phosphatidylcholine Docosahexaenoic Acid Content and Risk of Dementia and Alzheimer Disease
Archives of Neurology · 2006 · Vol. 63(11) · pp. 1545–1545
Ernst J. Schaefer✉(Tufts University)Vanina Bongard(Boston University)Alexa Beiser(Framingham Heart Study)Stefania Lamon‐Fava(Tufts University)Sander J. Robins(Boston University)Rhoda Au(Framingham Heart Study)Katherine L. Tucker(Framingham Heart Study)David J. Kyle(Framingham Heart Study)Peter W.F. Wilson(Jean Mayer Human Nutrition Research Center on Aging)Philip A. Wolf(Tufts University)
Abstract
The top quartile of plasma PC DHA level was associated with a significant 47% reduction in the risk of developing all-cause dementia in the Framingham Heart Study.
Fatty Acid Research and HealthFolate and B Vitamins ResearchBirth, Development, and HealthDementiaDocosahexaenoic acidInternal medicineQuartileConfidence intervalAlzheimer's diseaseMedicineRelative riskEndocrinologyGastroenterology
MeSH terms
AgedAged, 80 and overAlzheimer DiseaseDementiaDocosahexaenoic AcidsFemaleFollow-Up StudiesHumansMaleMental Status SchedulePhosphatidylcholinesProspective StudiesRiskIncidenceProportional Hazards Models
Funding
- U.S. Department of Agriculture
- Pfizer
- University of Connecticut
- National Institutes of Health
- National Institute on Aging
- National Heart, Lung, and Blood Institute
Citations
681
FWCI
27.88
field-weighted impact
References
28
Percentile
100%
vs. same field & year
Citations per year
Cited by
Alzheimer disease: Epidemiology, diagnostic criteria, risk factors and biomarkers
Biochemical Pharmacology · 2014 · 1,164 citations
Omega-3 fatty acids and coronary heart disease risk: Clinical and mechanistic perspectives
Atherosclerosis · 2008 · 551 citations
A Systemic Review of the Roles of n-3 Fatty Acids in Health and Disease
Journal of the American Dietetic Association · 2009 · 687 citations
Beneficial Outcomes of Omega-6 and Omega-3 Polyunsaturated Fatty Acids on Human Health: An Update for 2021
Nutrients · 2021 · 939 citations
References
The Clinical Dementia Rating (CDR)
Neurology · 1993 · 9,838 citations
Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.
Proceedings of the National Academy of Sciences · 1993 · 4,266 citations
Reproducibility and Validity of an Expanded Self-Administered Semiquantitative Food Frequency Questionnaire among Male Health Professionals
American Journal of Epidemiology · 1992 · 2,121 citations
Consumption of Fish and n-3 Fatty Acids and Risk of Incident Alzheimer Disease
Archives of Neurology · 2003 · 1,125 citations
Clinical diagnosis of Alzheimer's disease
Neurology · 1984 · 27,910 citations
Improved procedure for the extraction of lipids from human erythrocytes
Journal of Lipid Research · 1965 · 1,047 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.