reviewTop 1% cited

Sperm DNA damage is associated with an increased risk of pregnancy loss after IVF and ICSI: systematic review and meta-analysis

Human Reproduction · 2008 · Vol. 23(12) · pp. 2663–2668

Armand Zini✉(St Mary's Hospital)Jason Boman(St Mary's Hospital)Éric Belzile(St Mary's Hospital)Antonio Ciampi(St Mary's Hospital)

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Abstract

In conclusion, sperm DNA damage is associated with a significantly increased risk of pregnancy loss after IVF and ICSI. These data provide a clinical indication for the evaluation of sperm DNA damage prior to IVF or ICSI and a rationale for further investigating the association between sperm DNA damage and pregnancy loss.

Sperm and Testicular Function Reproductive Biology and Fertility Reproductive Health and TechnologiesPregnancyIntracytoplasmic sperm injectionGynecologyAndrologyMedicineObstetricsSpermIn vitro fertilisationBiologyGenetics

MeSH terms

Abortion, SpontaneousDNA DamageFemaleFertilization in VitroHumansMalePregnancyPregnancy OutcomeSpermatozoaOdds RatioTreatment OutcomeSperm Injections, Intracytoplasmic

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561

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30.43

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Cited by

Correlation of sperm DNA integrity with other semen parameters and analyse the role of abnormal sperm DNA in evaluation of infertility