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Sperm DNA integrity assessment in prediction of assisted reproduction technology outcome

Human Reproduction · 2006 · Vol. 22(1) · pp. 174–179

M. Bungum✉(Skive Hospital)Peter Humaidan(Skive Hospital)Anna Axmon(Lund University)Maria Spano(ENEA Casaccia Research Centre)Leif Bungum(Skive Hospital)Juris Ērenpreiss(Lund University)A. Giwercman(Scania (Sweden))

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Abstract

DFI can be used as an independent predictor of fertility in couples undergoing IUI. As a result, we propose that all infertile men should be tested with SCSA as a supplement to the standard semen analysis. When DFI exceeds 30%, ICSI should be the method of choice.

Assisted Reproductive Technology and Twin Pregnancy Sperm and Testicular Function Reproductive Biology and FertilityGynecologyInseminationAndrologyFertilityBiologyIntrauterine inseminationAssisted reproductive technologySpermPregnancyDNA fragmentation

MeSH terms

AdultFemaleFertilization in VitroFlow CytometryHumansMalePredictive Value of TestsPregnancyPregnancy OutcomeSpermatozoaCohort StudiesSperm Injections, IntracytoplasmicReproductive Techniques, AssistedDNA Fragmentation

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Correlation of sperm DNA integrity with other semen parameters and analyse the role of abnormal sperm DNA in evaluation of infertility