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Vitamin C Enhances the Generation of Mouse and Human Induced Pluripotent Stem Cells

Cell stem cell · 2010 · Vol. 6(1) · pp. 71–79

Miguel A. Esteban✉(Chinese Academy of Sciences)Tao Wang(Chinese Academy of Sciences)Baoming Qin(Chinese Academy of Sciences)Jiayin Yang(Chinese Academy of Sciences)Dajiang Qin(Chinese Academy of Sciences)Jinglei Cai(Chinese Academy of Sciences)Wen Li(Chinese Academy of Sciences)Zhihui Weng(Chinese Academy of Sciences)Jiekai Chen(Chinese Academy of Sciences)Su Ni(Chinese Academy of Sciences)Keshi Chen(Chinese Academy of Sciences)Yuan Li(Chinese Academy of Sciences)Xiaopeng Liu(Chinese Academy of Sciences)Jianyong Xu(Chinese Academy of Sciences)Shiqiang Zhang(Chinese Academy of Sciences)Feng Li(Chinese Academy of Sciences)Wenzhi He(Chinese Academy of Sciences)Krystyna Labuda(Austrian Cluster for Tissue Regeneration)Yancheng Song(Sun Yat-sen University)Anja Peterbauer(Austrian Cluster for Tissue Regeneration)Susanne Wolbank(Austrian Cluster for Tissue Regeneration)Heinz Redl(Austrian Cluster for Tissue Regeneration)Mei Zhong(Nanfang Hospital)Daozhang Cai(Sun Yat-sen University)Lingwen Zeng(Chinese Academy of Sciences)Duanqing Pei(Chinese Academy of Sciences)

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Pluripotent Stem Cells Research Biomedical Ethics and Regulation Science, Research, and MedicineBiologyInduced pluripotent stem cellStem cellCell biologyVitaminHuman Induced Pluripotent Stem CellsCancer researchEmbryonic stem cellBiochemistryGene

MeSH terms

AnimalsAscorbic AcidCells, CulturedCytological TechniquesEmbryo, MammalianFibroblastsHumansCellular SenescenceMiceInduced Pluripotent Stem CellsCellular Reprogramming

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The Senescence-Related Mitochondrial/Oxidative Stress Pathway is Repressed in Human Induced Pluripotent Stem Cells