reviewTop 1% cited
Protein kinases — the major drug targets of the twenty-first century?
Nature Reviews Drug Discovery · 2002 · Vol. 1(4) · pp. 309–315
Philip Cohen✉(MRC Protein Phosphorylation and Ubiquitylation Unit)
Protein Kinase Regulation and GTPase SignalingPI3K/AKT/mTOR signaling in cancerChronic Lymphocytic Leukemia ResearchPhosphorylationKinaseDrugDrug developmentProtein phosphorylationProtein kinase ADrug discoveryPharmacologyDrug targetMedicine
MeSH terms
Imatinib MesylateAnimalsAnti-Inflammatory Agents, Non-SteroidalAntineoplastic AgentsBenzamidesEnzyme ActivationEnzyme InhibitorsHumansImmunosuppressive AgentsPiperazinesPyrimidinesProtein Kinase Inhibitors
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References
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Nature Cell Biology · 2002 · 1,120 citations
SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin‐1
FEBS Letters · 1995 · 2,089 citations
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