articleTop 1% cited
Staurosporine, a potent inhibitor of phospholipidCa++dependent protein kinase
Biochemical and Biophysical Research Communications · 1986 · Vol. 135(2) · pp. 397–402
Tatsuya Tamaoki✉(Kyowa Kirin (Japan))Hisayo Nomoto(Kyowa Kirin (Japan))ISAMI TAKAHASHI(Kyowa Kirin (Japan))Yuzuru Kato(Kyowa Kirin (Japan))Makoto Morimoto(Kyowa Kirin (Japan))Fusao Tomita(Kyowa Kirin (Japan))
Microbial Natural Products and BiosynthesisChemical synthesis and alkaloidsPlant biochemistry and biosynthesisStaurosporineProtein kinase CProtein kinase inhibitorIC50Protein kinase AKinaseChemistryHeLaBiochemistryMolecular biology
MeSH terms
AlkaloidsAnimalsBinding, CompetitiveBrainCell DivisionHeLa CellsHumansPhorbol EstersProtein BindingProtein Kinase CPhorbol 12,13-DibutyrateStaurosporineRats
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References
Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.
Journal of Biological Chemistry · 1982 · 4,754 citations
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