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ACETAMINOPHEN-INDUCED HEPATIC NECROSIS. II. ROLE OF COVALENT BINDING IN VIVO
Journal of Pharmacology and Experimental Therapeutics · 1973 · Vol. 187(1) · pp. 195–202
David J. Jollow✉(Lung Institute)John R. Mitchell(Lung Institute)William Z. Potter(National Heart Lung and Blood Institute)Dawn C. Davis(National Institutes of Health)J R Gillette(National Institutes of Health)B.B. Brodie(Lung Institute)
Drug-Induced Hepatotoxicity and ProtectionDrug Transport and Resistance MechanismsLiver Disease Diagnosis and TreatmentNecrosisIn vivoAcetaminophenMetaboliteChemistryMicrosomeCovalent bondPiperonyl butoxideBiochemistryPharmacology
MeSH terms
AcetaminophenAnimalsCarbon RadioisotopesCell NucleusCobaltLiverLiver DiseasesMaleMice, Inbred StrainsMicrosomes, LiverMitochondria, LiverNecrosisPhenobarbitalPiperonyl ButoxideProtein Binding
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