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The cut-off limits of the GH response to GH-releasing hormone-arginine test related to body mass index

European Journal of Endocrinology · 2005 · Vol. 153(2) · pp. 257–264

G. Corneli(University of Turin)Carolina Di Somma(SDN Istituto di Ricerca Diagnostica e Nucleare)Roberto Baldelli(University of Turin)Silvia Rovere(University of Turin)Valentina Gasco(University of Turin)Chiara Giulia Croce(University of Turin)Silvia Grottoli(University of Turin)Mauro Maccario(University of Turin)Annamaria Colao(University of Naples Federico II)Gaetano Lombardi(University of Naples Federico II)Ezio Ghigo(University of Turin)F. Camanni(University of Turin)Gianluca Aimaretti✉(University of Turin)

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Abstract

In conclusion the GHRH-ARG test is a reliable tool for the diagnosis of adult GH deficiency in lean, overweight and obese patients, provided that specific BMI-related cut-off limits are assumed.

Growth Hormone and Insulin-like Growth Factors Diabetes and associated disorders Thyroid Disorders and TreatmentsEndocrinologyInternal medicineArginineBody mass indexGrowth hormoneMedicineHormoneChemistryAmino acidBiochemistry

MeSH terms

AdultArginineDiagnostic Techniques, EndocrineFemaleHumansHypopituitarismInsulin-Like Growth Factor IMaleMiddle AgedSensitivity and SpecificityGrowth Hormone-Releasing HormoneReproducibility of ResultsBody Mass IndexHuman Growth Hormone

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316

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The GH/IGF1 axis and signaling pathways in the muscle and bone: mechanisms underlying age-related skeletal muscle wasting and osteoporosis