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The 70-gene prognosis-signature predicts disease outcome in breast cancer patients with 1–3 positive lymph nodes in an independent validation study
Breast Cancer Research and Treatment · 2008 · Vol. 116(2) · pp. 295–302
Stella Mook✉(Oncode Institute)Marjanka K. Schmidt(The Netherlands Cancer Institute)Giuseppe Viale(University of Milan)Giancarlo Pruneri(Indiana University School of Medicine)I. Eekhout(The Netherlands Cancer Institute)Arno Floore(Agendia (Netherlands))Annuska M. Glas(Agendia (Netherlands))Jan Bogaerts(European Organisation for Research and Treatment of Cancer)Fátima Cardoso(Institut Jules Bordet)Martine Piccart(Institut Jules Bordet)Emiel J. Rutgers(The Netherlands Cancer Institute)Laura J. van’t Veer(Agendia (Netherlands))
Breast Cancer Treatment StudiesHER2/EGFR in Cancer ResearchCancer Genomics and DiagnosticsBreast cancerMedicineOncologyLymphInternal medicineGene signatureDiseaseOutcome (game theory)Signature (topology)Cancer
MeSH terms
AdultAgedBreast NeoplasmsFemaleHumansLymphatic MetastasisMiddle AgedNeoplasm Recurrence, LocalPrognosisOligonucleotide Array Sequence AnalysisGene Expression ProfilingKaplan-Meier Estimate
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References
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Cancer · 1989 · 2,286 citations
Gene expression profiling predicts clinical outcome of breast cancer
Nature · 2002 · 9,574 citations
Strong Time Dependence of the 76-Gene Prognostic Signature for Node-Negative Breast Cancer Patients in the TRANSBIG Multicenter Independent Validation Series
Clinical Cancer Research · 2007 · 981 citations
Converting a breast cancer microarray signature into a high-throughput diagnostic test
BMC Genomics · 2006 · 495 citations
Validation and Clinical Utility of a 70-Gene Prognostic Signature for Women With Node-Negative Breast Cancer
JNCI Journal of the National Cancer Institute · 2006 · 1,223 citations
Repeated observation of breast tumor subtypes in independent gene expression data sets
Proceedings of the National Academy of Sciences · 2003 · 5,398 citations
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