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Critical Evaluation of Nanoparticle Tracking Analysis (NTA) by NanoSight for the Measurement of Nanoparticles and Protein Aggregates
Pharmaceutical Research · 2010 · Vol. 27(5) · pp. 796–810
Vasco Filipe✉(Leiden University)Andrea Hawe(Centre for Human Drug Research)Wim Jiskoot(Centre for Human Drug Research)
Abstract
NTA is a powerful characterization technique that complements DLS and is particularly valuable for analyzing polydisperse nanosized particles and protein aggregates.
Protein purification and stabilityDrug Solubulity and Delivery SystemsAdvanced Drug Delivery SystemsNanoparticle tracking analysisDynamic light scatteringDispersityNanoparticleParticle sizeDrug deliveryParticle (ecology)PolystyreneParticle aggregationProtein aggregation
MeSH terms
AlgorithmsExcipientsImmunoglobulin GLightParticle SizePolystyrenesProteinsScattering, RadiationSoftwareViscosityDrug Delivery SystemsNanotechnologyNanoparticles
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References
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Critical Evaluation of Nanoparticle Tracking Analysis (NTA) by NanoSight for the Measurement of Nanoparticles and Protein Aggregates
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