reviewTop 1% cited
Necrosis, a well-orchestrated form of cell demise: Signalling cascades, important mediators and concomitant immune response
Biochimica et Biophysica Acta (BBA) - Bioenergetics · 2006 · Vol. 1757(9-10) · pp. 1371–1387
Nele Festjens✉(Ghent University)Tom Vanden Berghe(Ghent University)Peter Vandenabeele(Ghent University)
Cell death mechanisms and regulationImmune Response and InflammationNeutrophil, Myeloperoxidase and Oxidative MechanismsProgrammed cell deathCell biologyNecrosisApoptosisNecroptosisBiologyPyroptosisCaspaseCrosstalkBiochemistry
MeSH terms
AnimalsCytoskeletonHumansNecrosisSignal TransductionCell DeathReactive Oxygen SpeciesInflammation Mediators
Funding
- Universiteit Gent
- Vlaamse regering
Citations
690
FWCI
17.78
field-weighted impact
References
254
Percentile
100%
vs. same field & year
Citations per year
Cited by
Lysosomal membrane permeabilization in cell death
Oncogene · 2008 · 1,388 citations
Cell death modalities: classification and pathophysiological implications
Cell Death and Differentiation · 2007 · 817 citations
Cell death by necrosis: towards a molecular definition
Trends in Biochemical Sciences · 2006 · 1,005 citations
Necroptosis, necrosis and secondary necrosis converge on similar cellular disintegration features
Cell Death and Differentiation · 2009 · 625 citations
Oxidative stress and left ventricular remodelling after myocardial infarction
Cardiovascular Research · 2008 · 516 citations
Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009
Cell Death and Differentiation · 2008 · 3,307 citations
References
Fas triggers an alternative, caspase-8–independent cell death pathway using the kinase RIP as effector molecule
Nature Immunology · 2000 · 1,899 citations
BCL-2 Is Phosphorylated and Inactivated by an ASK1/Jun N-Terminal Protein Kinase Pathway Normally Activated at G<sub>2</sub>/M
Molecular and Cellular Biology · 1999 · 998 citations
Oxyradicals and DNA damage
Carcinogenesis · 2000 · 1,881 citations
The CD95(APO-1/Fas) DISC and beyond
Cell Death and Differentiation · 2003 · 1,064 citations
Mitogen-activated protein kinases in apoptosis regulation
Oncogene · 2004 · 1,428 citations
Necrosis: a specific form of programmed cell death?
Experimental Cell Research · 2003 · 709 citations
The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy
Biochimica et Biophysica Acta (BBA) - Bioenergetics · 1998 · 1,382 citations
Elucidating the molecular mechanism of the permeability transition pore and its role in reperfusion injury of the heart
Biochimica et Biophysica Acta (BBA) - Bioenergetics · 1998 · 484 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.