articleTop 1% cited
Elucidating the molecular mechanism of the permeability transition pore and its role in reperfusion injury of the heart
Biochimica et Biophysica Acta (BBA) - Bioenergetics · 1998 · Vol. 1366(1-2) · pp. 79–94
Andrew P. Halestrap✉(University of Bristol)Paul M. Kerr(Bristol Royal Infirmary)Sabzali Javadov(Azerbaijan Medical University)K Woodfield(University of Bristol)
Cardiac Ischemia and ReperfusionMitochondrial Function and PathologyFuel Cells and Related MaterialsMitochondrial permeability transition poreANTBiophysicsChemistryMitochondrionInner mitochondrial membraneBinding siteConformational changeGlutathioneBiochemistry
MeSH terms
Mitochondrial ADP, ATP TranslocasesAdenosine TriphosphateAnimalsCalciumDeoxyglucoseHeartHumansMitochondria, HeartNecrosisPerfusionPermeabilityCalcium ChannelsMyocardial Reperfusion InjuryPropofolFree Radical Scavengers
Funding
- British Heart Foundation
- Royal Society
- Medical Research Council
Citations
484
FWCI
17.14
field-weighted impact
References
152
Percentile
99%
vs. same field & year
Citations per year
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References
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The Ca2+-induced membrane transition in mitochondria
Archives of Biochemistry and Biophysics · 1979 · 772 citations
Role of ubiquinone in the mitochondrial generation of hydrogen peroxide
Biochemical Journal · 1976 · 647 citations
The Ca2+-induced membrane transition in mitochondria
Archives of Biochemistry and Biophysics · 1979 · 848 citations
Transport of lactate and other monocarboxylates across mammalian plasma membranes
American Journal of Physiology-Cell Physiology · 1993 · 748 citations
JC‐1, but not DiOC<sub>6</sub>(3) or rhodamine 123, is a reliable fluorescent probe to assess Δ<i>Ψ</i> changes in intact cells: implications for studies on mitochondrial functionality during apoptosis
FEBS Letters · 1997 · 1,000 citations
Ubisemiquinone is the electron donor for superoxide formation by complex III of heart mitochondria
Archives of Biochemistry and Biophysics · 1985 · 1,200 citations
Propofol
Drugs · 1995 · 371 citations
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